List of Validated Methods

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Compound

Biological Matrix

Instrument

Abafungin

Human Plasma

LC-MS/MS

Acetylsalicylic Acid

Human Plasma

HPLC-UV

Acetylsalicylic Acid

Human Plasma

LC-MS/MS

Acetylsalicylic Acid

Pig Plasma

HPLC-UV

Acetylsalicylic Acid

Pig Tissue

HPLC-UV

Alfuzosine

Human Plasma

HPLC-Fluorescence

Aminosidine

Bovine Tissue

HPLC-ECD

Aminosidine

Pig Tissue

HPLC-ECD

Aminosidine

Chicken Tissue

HPLC-ECD

Aminosidine

Rabbit Tissue

HPLC-ECD

Aminosidine/Dihydrostreptomycine

Bovine Plasma

HPLC-ECD

Amitriptyline (Nortriptyline)

Human Plasma

HPLC-UV

Amlodipine

Human Plasma

LC-MS/MS

Amlodipine

Human Plasma

HPLC-UV

Amoxicillin

Human Plasma

HPLC-UV

Amoxicillin

Human Plasma

LC-MS/MS

Amoxicillin

Bovine Tissue

LC-MS/MS

Amoxicillin

Cat Plasma

LC-MS/MS

Amoxicillin

Dog Plasma

LC-MS/MS

Ampicillin

Human Plasma

HPLC-UV

Ampicillin

Human Plasma

LC-MS/MS

D-Arabinitol/ L-Arabinitol

Human Urine

GC-MS/NCI

Atenolol

Human Plasma

HPLC-Fluorescence

Atorvastatin

Human Plasma

HPLC-UV

Atorvastatin (2-Hydroxy-Atorvastatin)

Rat Plasma

LC-MS/MS

Atorvastatin (2-Hydroxy-/4-Hydroxy-Atorvastatin)

Human Plasma

LC-MS/MS

Azaperone

Pig Plasma

LC-MS/MS

Azaperone (Azaperol)

Pig Tissue

LC-MS/MS

Azithromycin

Human Plasma

LC MS/MS

Azithromycin

Human Plasma

HPLC-ECD

Bamipine

Human Plasma

LC-MS/MS

Benzylpenicillin

Bovine Plasma

LC-MS/MS

Benzylpenicillin

Cat Plasma

LC-MS/MS

Benzylpenicillin

Dog Plasma

LC-MS/MS

Benzylpenicillin

Pig Plasma

LC-MS/MS

Benzylpenicillin

Bovine Tissue

LC-MS/MS

Benzylpenicillin

Pig Tissue

LC-MS/MS

Benzylpenicillin

Turkey Tissue

LC-MS/MS

Benzylpenicillin

Bovine Milk

LC-MS/MS

BGP-15

Human Plasma

HPLC-UV

Bicalutamide

Human Plasma

LC-MS/MS

Budesonide

Human Plasma

LC-MS/MS

Bupranolol

Human Plasma

HPLC-UV

Buprenorphine

Human Plasma

LC-MS/MS

Caffeine

Human Plasma

HPLC-UV

Calcitriol

Human Plasma

GC-MS/EI

Candesartan

Human Plasma

HPLC-Fluorescence

Canrenone

Human Plasma

HPLC-UV

Captopril

Human Plasma

HPLC-UV

Carbidopa

Human Plasma

HPLC-ECD

Carprofen

Dog Plasma

HPLC-Fluorescence

Carvedilol

Human Plasma

HPLC-Fluorescence

Cefalexin

Dog Skin

HPLC-UV

Cefalexin

Dog Plasma

LC-MS/MS

Cefuroxime

Human Plasma

HPLC-UV

CER 002

Human Plasma

HPLC-UV

CER 002

Human Plasma

LC-MS/MS

Chlorphenamine

Human Plasma

HPLC-UV

Chlorpromazine

Human Plasma

LC-MS/MS

Chlorprothixene

Human Plasma

LC-MS/MS

Chlortetracycline/4-Epichlortetracycline

Pig Plasma

HPLC-UV

Ciclosporin

Human Plasma

LC-MS/MS

Cimetidine

Human Plasma

HPLC-UV

1,8-Cineole

Human Plasma

GC-MS

Ciprofloxacin

Human Plasma

HPLC-UV

Cisapride

Human Plasma

HPLC-UV

Clarithromycin

Human Plasma

HPLC-ECD

Clavulanic Acid

Human Plasma

LC-MS-MS

Clavulanic Acid

Human Plasma

HPLC-UV

Clavulanic Acid

Cat Plasma

LC-MS/MS

Clavulanic Acid

Dog Plasma

LC-MS/MS

Clenbuterol

Bovine Milk

LC-MS/MS

Clenbuterol

Horse Plasma

LC-MS/MS

Clindamycin

Human Plasma

LC-MS/MS

Clomipramine (Norclomipramine)

Dog Plasma

LC-MS/MS

Clopidogrel

Rat Plasma

LC-MS/MS

Clopidogrel (Clopidogrel Acid)

Human Plasma

LC-MS/MS

Colistin

Bovine Milk

HPLC-Fluorescence

CYC 682 (CYC 682/9)

Human Plasma

LC-MS/MS

CYC-202

Human Plasma

LC-MS/MS

CYC-202

Human Urine

LC-MS/MS

CYC-202

Monkey Plasma

LC-MS/MS

Dexamethasone

Bovine Milk

LC-MS/MS

Diclazuril

Pig Plasma

LC-MS/MS

Diclazuril

Pig Milk

LC-MS/MS

Diclazuril

Chicken Tissue

LC-MS/MS

Diclazuril

Turkey Tissue

LC-MS/MS

Diclofenac

Human Plasma

HPLC-UV

Diclofenac

Human Plasma

GC-MS

Digoxin

Human Plasma

ELISA

Dihydrostreptomycin

Bovine Milk

HPLC-ECD

Dihydrostreptomycin

Pig Tissue

HPLC-ECD

Dihydrotestosterone

Human Serum

LC-MS/MS

Diltiazem

Human Plasma

LC-MS/MS

Dipyridamole

Human Plasma

LC-MS/MS

Docetaxel

Dog Plasma

LC-MS/MS

Doxazosin

Human Plasma

HPLC-Fluorescence

Doxycycline

Human Plasma

HPLC-UV

Duloxetine

Human Plasma

LC-MS/MS

Ebastine (Carebastine)

Human Plasma

LC-MS/MS

Elgodipine

Human Plasma

HPLC-UV

Enalapril (Enalaprilat)

Dog Plasma

LC-MS/MS

Enalapril (Enalaprilat)

Human Plasma

GC-MS

Enalapril (Enalaprilat)

Human Plasma

LC-MS/MS

Enrofloxacin

Cat Plasma

LC-MS/MS

Enrofloxacin (Ciprofloxacin)

Dog Plasma

HPLC-Fluorescence

Erythromycin

Human Plasma

HPLC-ECD

Esomeprazole

Human Plasma

HPLC-UV

Etodolac

Human Plasma

HPLC-Fluorescence

Felodipine

Human Plasma

GC-MS/NCI

Fenofibric Acid

Human Plasma

HPLC-UV

Fenoprofen

Human Plasma

LC-MS/MS

Flubendazole (Metabolite M7)

Pig Tissue

LC-MS/MS

Fluconazole

Human Plasma

HPLC-UV

Flunixin

Horse Plasma

LC-MS/MS

Fluoxetine (Norfluoxetine)

Human Plasma

HPLC-Fluorescence

Flurbiprofen

Human Plasma

HPLC-Fluorescence

Formaldehyde

Human Urine

GC-NPD

Formaldehyde

Human Plasma

GC-NPD

Framycetin

Bovine Milk

LC-MS/MS

Framycetin

Bovine Plasma

LC-MS/MS

Framycetin

Bovine Milk

HPLC-ECD

Framycetin

Bovine Tissue

LC-MS/MS

Furosemide

Human Plasma

HPLC-UV

Gabapentin

Human Plasma

LC-MS/MS

Gabapentin

Human Plasma

HPLC-Fluorescence

Glutathione

Human Blood

HPLC-ECD

Glyceroltrinitrate, GTN (1,2-GTN, 1,3-GTN)

Human Plasma

GC-MS/NCI

Granisetron

Human Plasma

HPLC-Fluorescence

Haloperidol

Human Plasma

LC-MS/MS

Heparin

Human Blood

aPTT, Factor Xa

Hydrochlorothiazide

Human Plasma

HPLC-UV

Hydrochlorothiazide

Human Plasma

LC-MS/MS

Hydrocodone

Human Plasma

LC-MS/MS

Hydrocortisone

Human Plasma

LC-MS/MS

Hydrocortisone

Human Plasma

HPLC-UV

Hydromorphone

Human Plasma

LC-MS/MS

8-α-Hydroxymutilin

Turkey Tissue

GC-MS/EI

Hypericin/Pseudohypericin

Human Plasma

HPLC-Fluorescence

Ibuprofen

Human Plasma

HPLC-UV

Ibuprofen

Human Plasma

LC-MS/MS

Indometacin

Human Plasma

HPLC-UV

INH

Human Plasma

HPLC-ECD

Irbesartan

Human Plasma

HPLC-Fluorescence

Isoniazid

Human Plasma

HPLC-ECD

Isosorbid-5-Mononitrat

Human Plasma

GC-ECD

Isosorbiddinitrat (IS-5-MN, IS-2-MN)

Human Plasma

GC-ECD

Ivermectin

Pig Plasma

HPLC-Fluorescence

Keto-Boswellic Acid/Acetyl-Keto-Bowellic Acid

Human Plasma

LC-MS/MS

Lamotrigine

Human Plasma

HPLC-UV

Lamotrigine

Human Plasma

LC MS/MS

Lercanidipine

Human Plasma

LC-MS/MS

Levetiracetam

Human Plasma

LC-MS/MS

Levodopa

Human Plasma

HPLC-ECD

d-Limonene

Human Plasma

GC-MS

Lincomycin

Pig Tissue

LC-MS/MS

Linezolid

Human Plasma

HPLC-UV

Lisinopril

Human Plasma

LC-MS/MS

Loratadine (Desoxyloratadine)

Human Plasma

HPLC-UV

Lornoxicam

Human Plasma

HPLC-UV

Losartan

Human Plasma

HPLC-Fluorescence

Losartan (Losartan Carboxy Acid)

Human Plasma

LC-MS/MS

Lovastatin (Lovastatin Acid)

Human Plasma

GC-MS/EI

Lovastatin (Lovastatin Acid)

Human Plasma

LC-MS/MS

Meloxicam

Bovine Plasma

HPLC-UV

Meloxicam

Pig Plasma

HPLC-UV

Meloxicam

Bovine Tissue

LC-MS/MS

Meloxicam

Bovine Milk

HPLC-UV

Memantine

Human Plasma

LC-MS/MS

Metformin

Human Plasma

LC-MS/MS

Metformin

Human Plasma

HPLC-UV

Methenamine

Human Plasma

GC-NPD

Methenamine

Human Urine

GC-NPD

Methylphenidate

Human Plasma

LC-MS/MS

L-Methylphenidate/D-Methylphenidate

Human Plasma

LC-MS/MS

Metoprolol

Human Plasma

HPLC-Fluorescence

Midazolam

Human Plasma

GC-ECD

Midazolam (Hydroxymidazolam)

Human Plasma

LC-MS/MS

Molsidomine (SIN-1)

Human Plasma

HPLC-UV

Montelukast

Human Plasma

HPLC-Fluorescence

Morphine (Morphine-3-ß-D-Glucuronide, Morphine-6-ß-D-Glucuronide)

Human Plasma

LC-MS/MS

Moxifloxacin

Human Plasma

HPLC-Fluorescence

Mycophenolic Acid

Human Plasma

HPLC-UV

Myrtol

Human Plasma

GC-MS

Naproxen

Human Plasma

HPLC-Fluorescence

Nebivolol

Human Plasma

LC-MS/MS

Nevirapine

Human Plasma

HPLC-UV

Nifedipine

Human Plasma

GC-ECD

Nimodipine

Human Plasma

GC-ECD

Nitrendipine

Human Plasma

GC-ECD

Ofloxacin

Human Plasma

HPLC-UV

Olmesartan

Human Plasma

LC-MS/MS

Omeprazole

Human Plasma

HPLC-UV

Ornidazole

Human Plasma

HPLC-UV

Oxycodone

Human Plasma

LC-MS/MS

Oxytetracycline

Plasma

HPLC-UV

Oxytetracycline

Plasma

HPLC-UV

Oxytetracycline/4-Epioxytetracycline

Chicken Egg

LC-MS/MS

Oxytetracycline/4-Epioxytetracycline

Chicken Tissue

LC-MS/MS

Oxytetracycline/4-Epioxytetracycline

Chicken Plasma

LC MS/MS

Pantoprazole

Human Plasma

LC-MS/MS

Paracetamol

Human Plasma

HPLC-UV

Penicillin V

Human Plasma

LC-MS/MS

Pentoxifylline (5-OH-Pentoxifylline)

Human Plasma

HPLC-UV

Perindopril (Perindoprilat)

Human Plasma

LC-MS/MS

Pimobendan (UD-CG 115 BS)

Dog Plasma

HPLC-Fluorescence

Pimobendan (UD-CG 212)

Cat Plasma

HPLC-Fluorescence

α-Pinene

Human Plasma

GC-MS

Pioglitazone

Human Plasma

LC-MS/MS

Piroxicam

Human Plasma

HPLC-UV

Polidocanol

Human Plasma

LC-MS/MS

Pramipexole

Human Plasma

LC-MS/MS

Pravastatin (3-Hydroxypravastatin)

Human Plasma

LC-MS/MS

Prazosin

Human Plasma

HPLC-Fluorescence

Prednisolone

Human Plasma

HPLC-UV

Prednisolone/Hydrocortisone

Bovine Plasma

LC-MS/MS

Progesterone

Saliva

LC-MS/MS

Propafenon

Human Plasma

HPLC-UV

Propranolol

Human Plasma

HPLC-Fluorescence

Quetiapine

Human Plasma

LC-MS/MS

Ramipril (Ramiprilat)

Human Plasma

LC-MS/MS

Ramipril (Ramiprilat)

Dog Plasma

LC-MS/MS

Ranitidine

Human Plasma

HPLC-UV

Roxithromycin

Human Plasma

LC-MS/MS

Salbutamol

Human Plasma

HPLC-UV

Salicylic Acid

Human Plasma

HPLC-UV

Salicylic Acid

Pig Plasma

HPLC-UV

Salicylic Acid

Pig Tissue

HPLC-UV

Salicylic Acid

Human Plasma

LC-MS/MS

Sibutramine (Metabolite M1 and M2)

Human Plasma

LC-MS/MS

Sildenafil (N-desmethylsildenafil)

Human Plasma

HPLC-UV

Silibinin

Human Plasma

HPLC-UV

Simvastatin (Simvastatin Acid)

Human Plasma

LC MS/MS

Simvastatin (Simvastatin Acid)

Human Plasma

GC-MS/EI

Simvastatin (Simvastatin Acid)

Human Urine

LC MS/MS

Spironolactone

Human Plasma

HPLC-UV

Streptomycin

Bovine Milk

HPLC-ECD

Sulbactam

Human Plasma

HPLC-UV

Sulbactam

Human Plasma

LCMS/MS

Sulfadoxine

Pig Plasma

LC-MS/MS

D-Silymarine/ L-Silymarine

Human Plasma

HPLC-UV

Tadalafil

Human Plasma

HPLC-UV

Tamsulosin

Human Plasma

HPLC-Fluorescence

Testosterone

Human Serum

LC-MS/MS

Tetrazepam

Human Plasma

GC-ECD

Theophylline

Human Plasma

HPLC-UV

Tiamulin

Turkey Tissue

LC-MS/MS

Tiamulin

Chicken Egg

LC-MS/MS

Tiapride

Human Plasma

HPLC-UV

Tolterodine

Human Plasma

LC-MS/MS

Torasemide

Human Plasma

HPLC-UV

R-Tranylcypromine/S-Tranylcypromine

Human Plasma

LC-MS/MS

Triamcinolone Acetonide

Human Plasma

HPLC-UV

Trimetazidine

Human Plasma

LC-MS/MS

Trimethoprim

Pig Plasma

LC-MS/MS

Tylosine

Pig Plasma

HPLC-UV

Tylosine

Pig Tissue

LC-MS/MS

Valsartan

Human Plasma

HPLC-Fluorescence

Venlafaxine

Human Plasma

HPLC-UV

Verapamil (Norverapamil)

Human Plasma

HPLC-Fluorescence

Xamoterol

Human Plasma

HPLC-Fluorescence

Zolpidem

Human Plasma

LC-MS/MS